The event is scheduled for April 26 at 6 p.m. at the high school. There is no charge to attend, but donations are encouraged.
Youth teams coached by teacher and former college basketball player Tiffany Niemeyer will face each other at half time.
There will also be concessions, a silent auction and Mule Bingo.
The two alumni teams will be represented by former Mule players from the classes of 1983 to 2013.